Acoustic trauma-induced auditory cortex enhancement and tinnitus

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Reorganization of auditory cortex in tinnitus.

Magnetic source imaging was used to determine whether tonotopy in auditory cortex of individuals with tinnitus diverges from normative functional organization. Ten tinnitus subjects and 15 healthy controls were exposed to four sets of tones while magnetoencephalographic recordings were obtained from the two cortical hemispheres in sequence. A marked shift of the cortical representation of the t...

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Immediate manifestation of acoustic trauma in the auditory cortex is layer specific and cell type dependent.

Exposure to loud sounds damages the auditory periphery and induces maladaptive changes in central parts of the auditory system. Diminished peripheral afferentation and altered inhibition influence the processing of sounds in the auditory cortex. It is unclear, however, which types of inhibitory interneurons are affected by acoustic trauma. Here we used single-unit electrophysiological recording...

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ژورنال

عنوان ژورنال: Journal of Otology

سال: 2014

ISSN: 1672-2930

DOI: 10.1016/j.joto.2014.11.001